In the Application of Intravenous Infusion, Have You Selected the Infusion Set Correctly?

An infusion set is a fluid delivery line that connects an infusion bottle/bag to an intravenously inserted catheter. At present, various types and uses of infusion sets have appeared in clinical practice, which provides the possibility of refining the infusion work and provides a good infusion route for the application of various drugs. How to choose a suitable infusion set has become a major problem for medical staff. BQ+ has compiled the following factors for you to consider when choosing an infusion set for your reference.

Disposable infusion sets are commonly used consumables in intravenous infusion therapy, and their main materials can be divided into polyvinyl chloride (PVC), polyolefin thermoplastic elastomer (TPE), ultra-low density polyethylene (PE) and polypropylene (PP), and so on.

Since the disposable infusion set is in direct contact with the drug, the adsorption of the drug by its material has increasingly become a focus of attention. Among them, PVC infusion sets have been widely controversial because of the plasticizer dioctyl phthalate (DEHP). DEHP can accumulate in tissues, blood, and body fluids and cause liver toxicity and reproductive toxicity. DEHP is an endogenous interference. Factors also exist carcinogens.

Clinical nurses need to understand the characteristics of disposable infusion set materials, as well as commonly used drugs that are easily absorbed by different materials, which is conducive to ensuring the effectiveness and safety of the clinical medication. Medications recommended for infusion in non-PVC infusion sets are:

1. Antitumor drugs: paclitaxel injection, fluorouracil injection, doxorubicin hydrochloride liposome injection, etc.;

2. Cardiovascular drugs: nimodipine injection, done, nitroglycerin injection, etc.;

3. Sedative and analgesic drugs: diazepam injection, chlorpromazine injection, flurbiprofen axetil injection, etc.;

4. Antibacterial drugs: itraconazole injection, ciprofloxacin injection, meropenem for injection, etc.;

5. Others: insulin injection, fat-containing emulsion preparation, dexamethasone injection, etc.

The infusion set is divided into ordinary infusion set and precision filter infusion set. The industry standard for intravenous therapy interprets the use of infusion sets and additional infusion devices, which requires that "precision filter infusion sets should be used when an infusion of fat emulsions, chemotherapeutic drugs, and traditional Chinese medicine preparations".

The American "Standard of Nursing Practice for Infusion Therapy" has a higher standard recommendation for parenteral nutrition infusion: "When entering parenteral nutrition without fat emulsion, a 0.2μm filter should be used. Entering parenteral nutrition containing fat emulsion (3-in-1 formulation), a 1.2μm filter should be used to reduce the risk of microbial, sediment, or particle contamination.

The particles in the infusion refer to the small particles of impurities that are polluted by various means during the production or clinical use of the medicinal solution, and the diameter is mainly between 1-25μm. Infusion of microparticles can cause phlebitis, vascular embolism, granuloma formation, and pyrogen-like reactions.

At present, ordinary disposable infusion sets limit the terminal filter infusion set to 15-20μm, which cannot achieve the purpose of intercepting harmful particles in the infusion solution. The pore size of the filter membrane of the precision filtration infusion device is less than or equal to 5μm.

When the medicinal liquid reaches the precision filtration device, the insoluble particles are intercepted by the precision filtration device, thereby effectively preventing the insoluble particles in the medicinal solution from entering the blood and reducing the potential harm or damage caused by the particles to the patient. direct harm, so as to achieve the purpose of treatment.

Precision filtration infusion sets are more expensive than ordinary infusion sets and are mostly made of non-PVC materials. They are suitable for most drugs and ensure the safety of infusion, and are widely used in clinical practice.

If the infusion of the precision filter infusion set is not smooth during use, it should be checked whether the side hole of the infusion set is blocked by rubber particles and whether the input liquid volume exceeds 2,000 ml. When the particles in the filter disc exceed the saturation volume, the filter hole will be completely closed. If blocked, the infusion set should be replaced.

Avoid air in the filter disc. When the infusion tube is used for the first time, the air should be exhausted. Observe frequently to avoid emptying of the medicine.

During the infusion process, due to the different properties of the drugs, there are different requirements in the use process. Some drugs are easily decomposed when exposed to light, which reduces the efficacy of the drugs, such as some antitumor drugs, antibiotics, antihypertensive drugs, and vasodilators. Drugs, water-soluble vitamins, etc., so needs to be protected from light during the infusion process.

The pipeline and a dripping pot of the disposable light-proof infusion set adopt a two-color molding process. The liquid contact layer (inner layer) is produced with transparent materials, and the light-proof layer (outer layer) is produced with light-proof raw materials, which can effectively avoid the decomposition of photosensitivity drugs.

When using light-proof drugs, the external light-proof bag for injection is equipped with a disposable light-proof infusion set, and attention should be paid to whether there is a precision filter device to reduce the input of infusion particles and infusion reactions.

Fat-soluble liquids and drugs such as fat milk should not be infused if they are contained, and alternative products should be used as far as possible for high-risk groups (newborns, prepubertal men, pregnant and lactating women).

with a flow setting fine-tuning device, the regulator scale is accurate, the flow rate is constant, and the safety and effectiveness of the drug are improved. The use of wheel clips to control the speed of ordinary infusion sets can easily lead to errors, and requires high-frequency monitoring and correction by nurses; infusion pumps are expensive and limit activities such as transferring patients to departments and hospitals.

This infusion set is accurate, safe, and convenient, with an adjustable range of 5-250ml/h. It is suitable for critically ill patients, pediatric infusion, and patients with heart failure to control the infusion volume. It is suitable for chemotherapy drugs, electrolytes, antibiotics, etc. drug.

It is a special infusion device set up to adapt to blood and its products. The domestic blood transfusion device pipeline and blood transfusion funnel are basically made of polyvinyl chloride (PVC), and the filter pore size is 170μm -260μm.

If the pore size is too small, it is easy to be blocked by micro polymers of platelets and leukocytes in blood cells, which affects the effective filtering area. In view of the PVC material of the blood transfusion set and the large filter aperture, it is not suitable for infusion.

With the increasing clinical demand, multi-functional infusion sets on the market continue to come out, adding functions such as automatic exhaust and automatic liquid stop, and the price also rises.

BQ+ believes that in clinical practice, it is necessary to select the appropriate infusion set on the premise of saving medical costs according to the patient's treatment plan, the nature of the drug used, the patient's economic factors, etc., to avoid the reduction of drug efficacy or even toxicity due to the material of the infusion set. We hope that our infusion set can become a healthy channel for patients and ensure the safety of patient infusion!

As a medical product manufacturer with extensive experience, BQ+ has developed and manufactured products that have passed various authoritative safety certifications and fully comply with strict medical requirements. We uphold a responsible attitude towards users and patients and control the quality of our products in an all-around way. Our products are also sold all over the world, if you want to buy our light-proof infusion set, please contact us immediately!